3 and 5 alkyl and phenyl 4-(hydroxy or acyloxy)-alkyl substitute

Details 3 and 5 alkyl and phenyl 4-(hydroxy or acyloxy)-alkyl substitute 3 and 5 alkyl and phenyl 4-(hydroxy or acyloxy)-alkyl substitute

1994-04-15

1995-09-19

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549321, 549323, C07F 909, C07D30740

Patent

active

054516862

ABSTRACT:
Novel anti-inflammatory furanone compounds have the following formula: ##STR1## where R.sub.1 independently is H, or alkyl of 1 to 9 carbons and n is an integer having the values of 1 or 2, and where when n is 1 the R.sub.1 group is attached to the 5 position of the 2-furanone, when n is 2 then R.sub.1 is attached to both the 3 and 5 positions, with the proviso that when n is 1 then R.sub.1 is not H; Y.sub.1 is H, alkyl of 1 to 20 carbons, phenyl C.sub.1 -C.sub.20 alkyl, C.sub.1 -C.sub.20 alkenyl containing one or more olefinic bonds, where R.sub.3 is H, C.sub.1 -C.sub.20 alkyl, C.sub.1 -C.sub.20 alkenyl containing one or more olefinic bonds, phenyl, halogen substituted phenyl or C.sub.1 -C.sub.6 alkyl substituted phenyl, with the proviso that when Y.sub.1 is CO--OR.sub.3 or CONHR.sub.3 then R.sub.3 is not hydrogen; Y.sub.2 is H, an alkyl group of 1 to 25 carbons, or phenyl.

REFERENCES:
patent: 2359096 (1944-09-01), Elderfield
patent: 2359208 (1944-09-01), Elderfield
patent: 4447445 (1984-05-01), Jacobs
patent: 4786651 (1988-11-01), Wheeler
patent: 4789749 (1988-12-01), Jacobs et al.
patent: 4855320 (1989-08-01), Chatterjee et al.
patent: 4874782 (1989-10-01), Bonjouklian et al.
patent: 4916241 (1990-04-01), Hayward et al.
patent: 4935530 (1990-06-01), Lee
patent: 5013850 (1991-05-01), Lee
patent: 5037811 (1991-08-01), Lee
patent: 5043457 (1991-08-01), Lee
patent: 5045564 (1991-09-01), Lee
patent: 5082954 (1992-01-01), Lee
patent: 5112853 (1992-05-01), Garst
patent: 5134128 (1992-07-01), Lee et al.
patent: 5169963 (1992-12-01), Lee
patent: 5171863 (1992-12-01), Lee et al.
patent: 5171864 (1992-12-01), Lee
patent: 5183906 (1993-02-01), Lee et al.
patent: 5212172 (1993-05-01), Lee
patent: 5225571 (1993-07-01), Lee
patent: 5258400 (1993-11-01), Garst et al.
patent: 5268387 (1993-12-01), Garst
patent: 5298633 (1994-03-01), Lee et al.
patent: 5322953 (1994-06-01), Lee et al.

Affiliated with

Also associated with

Rating

3 and 5 alkyl and phenyl 4-(hydroxy or acyloxy)-alkyl substitute does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3 and 5 alkyl and phenyl 4-(hydroxy or acyloxy)-alkyl substitute, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3 and 5 alkyl and phenyl 4-(hydroxy or acyloxy)-alkyl substitute will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1829292