3- and 5-[3-(1-arylureido)]-1,2,4-triazoles

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514384, 514218, 514252, 514376, 514377, 514374, 514369, 514370, 514371, 514365, 514316, 514318, 514326, 514333, 514336, 514340, 514341, 514342, 514269, 514275, 514256, 514272, 514274, 514273, 5142278, 5142318, 5142362, 540575, 548265, 548268, 548233, 548235, 548236, 548234, 548232, 548230, 548229, 548228, 548227, 548226, 548225, 548194, 548183, 548195, 548184, 548185, 548196, 548187, 548188, 548190, 548191, 548192, 548266, 548267, 548264, 544357, 544360, 544364, 544369, 544370, 544371, 544366, 544365, 54429

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active

RE0331252

ABSTRACT:
##STR1## This invention relates to [1-aryl-4-hydrazinyl-1,2-dihydro-1,3,5-triazin-2-ones and 2-thiones] 3- and 5-[3-(1-arylureido)] -1,2,4-triazoles and 3- and 5-[3-(1-(arylthioureido.Iadde nd.)]-triazoles of Formula I, processes for their preparation, isobiuret and 4-alkoxy-s-triazinone preparative intermediates, and methods of treating physiological disorders in humans and animals, in particular, cardiovascular disorders, including hypertension.

REFERENCES:
patent: 3144460 (1964-08-01), Hosler et al.
patent: 4246409 (1981-01-01), Douglas et al.
patent: 4338441 (1982-07-01), Douglas et al.
patent: 4406897 (1983-09-01), Campbell et al.

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