3-aminoquinazolin-2,4-dione antibacterial agents

Details 3-aminoquinazolin-2,4-dione antibacterial agents 3-aminoquinazolin-2,4-dione antibacterial agents

2006-08-22

2006-08-22

Rao, Deepak (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S252170, C514S266200, C514S266220, C514S266300, C514S266310, C544S119000, C544S284000, C544S285000

Reexamination Certificate

active

07094780

ABSTRACT:
Antibacterial 3-aminoquinazolin-2,4-diones have formula (I) wherein: R1and R3include alkyl, alkenyl, cycloalkyl, aryl, hetero-cyclic, and heteroaryl; R5, R6, and R8include H, alkyl, alkoxy, halo, NO2, CN, NH2, alkyl and dialkylamino; R7includes hydrogen, alkyl, cycloalkyl, hetero-cyclic, fused heterocyclic, aryl and fused aryl; J and K are C or N; and pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 35619 (1981-09-01), None
patent: 2097784 (1982-11-01), None
patent: WO 9414809 (1994-07-01), None
patent: WO 9818781 (1998-05-01), None
patent: WO 9921840 (1999-05-01), None
patent: WO 9961444 (1999-12-01), None
Snyder et al., PubMed Abstract (J Med Liban. 48(4):208-14) Jul.-Aug. 2000.
Chemical Abstracts, Abstract No. 237941k, vol. 133:17 (Oct. 23, 2000).
Garcia-Quintana, H.G., et al., Study of benzotriaxepines and quinazolines obtained by synthesis on bacterial populations, J. Vet. Med., Series B, vol. 34(5): 341-346 (1987).
Kornet, M.J., et al., Synthesis of 3-amino-2-4 (1H, 3H)-quinazolinediones for testing as anticonvulsants, J. Hetero. Chem., vol. 21(5): 1533-1535 (1984).
Langis, C., The synthesis of 1,3,4-benzotriazepine-1H-2,5-diones, Chim. Ther., vol. 2: 349-351 (1967).
Peet, N.P., et al., Synthesis of 3,4-dihydro-1H-1,3,4-benzotriazepine,2,5-diones, J. Org. Chem., vol. 40(13):1909-1914 (1975).
Baronnet, R., et al., Synthesis and pharmacodynamics of 3-dialkylamino-1H, 3H-quinazoline-2,4-diones and derivatives, Eur. J. Med. Chem.—Chim. Ther., vol. 18(3):241-247 (1983).
Davidson, J.S., The preparation of 5-(2-aminophenyl)-1,3,4-oxadiazol-2(3H)-one and its rearrangement to 3-amino-2,4(1H, 3H)-quinazolinedione, Monatshefte fur Chem., vol. 115(5):565-572 (1984).
Zhuo, J-C., et al., Boron-containing heterocycles: Synthesis, Structures, and Benzoborauracil Nucleoside, J. Org. Chem., vol. 64(26):9566-9574 (1999).
Database Caplus, Chemical Abstract Service, AN—1998:699954; Bull. Korean Chem. Soc., vol. 19(10):1117-1119 (1998).
Database Caplus, Chemical Abstract Service, AN—1996:275827; J. Hetero. Chem., vol. 33(4):1131-1135 (1996).
Database Caplus, Chemical Abstract Service, AN—1997:468311; J. Org. Chem., vol. 45(15):2551-2556 (1977).
Database Caplus, Chemical Abstract Service, AN—1968:2872; Helv. Chim. Acta., vol. 50(7):2019-2022 (1968).
Database Caplus, Chemical Abstract Service, AN—1997:522336; Arch. Pharm., vol. 330(5): 129-134 (1997).
Database Crossfile, Beilstein Reg. No. 214132 (1910); Chem. Berich., vol. 43: 1236 (1910).
Database Crossfile, Beilstein Reg. No. 657750 (1965); Chem. Berich., vol. 98: 1505-1510 (1965).
Database Crossfile, Beilstein Reg. No. 169392 (1967); Chem. Ther., vol. 2: 1236 (1967).

Affiliated with

Also associated with

Rating

3-aminoquinazolin-2,4-dione antibacterial agents does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3-aminoquinazolin-2,4-dione antibacterial agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3-aminoquinazolin-2,4-dione antibacterial agents will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3615821