3-aminopyrroles, methods for their synthesis and for their pharm

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514326, 514412, 514422, 514423, 544141, 546208, 548516, 548518, 548532, A61K 3140, A61K 31445, A61K 31535

Patent

active

055020518

ABSTRACT:
The invention is directed to 3-aminopyrroles of formula I, which are largely new, to methods for the preparation and to their use as medicinal agents and preparations, as well as to anti-convulsive or analgesic preparations containing these 3-aminopyrroles.
Disubstituted and monosubstituted amino groups are claimed as 3-amino substituents.
The invention pursues the objective of developing largely new 3-aminopyrroles, which have CNS activity, particularly ones which anti-convulsive or analgesic properties, as well as methods for their preparation and their use as medicinal preparations.
Pursuant to the invention, the synthesis is carried out by cyclizing open-chain precursors, such as aminoacrylic acid derivative, or by modifying pyrroles.

REFERENCES:
patent: 4198502 (1980-04-01), Tarzia et al.
Knoll, et al.; Chimija Geterociklicheskih Soedinenijg (1985), No. 5, pp. 628-630 (Synthesis ester of substituted .beta.-aminopyrrole-2-carboxylis acids from thioacrylic acids and alycine ethers.
Tarzia, et al.; Farmaco, Ed. Sci. (1984), 39(6), pp. 538-558; Synthesis and pharmacological evalution of a series of analgesic and antiinflammatory 4-aminopyrroles.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

3-aminopyrroles, methods for their synthesis and for their pharm does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3-aminopyrroles, methods for their synthesis and for their pharm, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3-aminopyrroles, methods for their synthesis and for their pharm will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-915746

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.