3-aminopropoxyphenyl derivatives, their preparation and pharmace

Details 3-aminopropoxyphenyl derivatives, their preparation and pharmace 3-aminopropoxyphenyl derivatives, their preparation and pharmace

1991-07-30

1993-09-07

Chan, Nicky

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3135

Patent

active

052429431

ABSTRACT:
##STR1## The compounds of Formula I and their physiologically hydrolysable derivatives, in which at least one hydroxy group is in esterified form, and their salts, elicit highly cardioselective beta 1 adrenoceptor blockade, and in most cases cardiospecific blockade, and relevant cardiotonic activity. These compounds can be used as therapeutic agents. One obtains these compounds by 3-amino-2-oxypropylation of the respective substituted phenol.

REFERENCES:
patent: 4661513 (1987-04-01), Berthold et al.

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