3-aminopiperidines and 3-aminoquinuclidines as inhibitors of...

Details 3-aminopiperidines and 3-aminoquinuclidines as inhibitors of... 3-aminopiperidines and 3-aminoquinuclidines as inhibitors of...

2004-05-25

2008-10-07

Seaman, D. Margaret (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S318000, C514S326000, C514S329000, C546S137000, C546S244000

Reexamination Certificate

active

07432280

ABSTRACT:
The present invention provides compounds of formula (I)and pharmaceutically acceptable salts thereof, which are useful for the inhibition of the uptake of one or more physiologically active monoamines (serotonin, norepinephrine, and dopamine).

REFERENCES:
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patent: 2321890 (1977-03-01), None
patent: WO 02/16356 (2002-02-01), None
patent: 03/037271 (2003-05-01), None
patent: WO 2004/035574 (2004-04-01), None
Roberts et al., Human Mutation, 2000, vol. 16, pp. 77-85.
De Costa, et al., “Synthesis and Evaluation of Conformationally RestrictedN-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-2-(1- pyrrolidinyl)ethylamines at σ Receptors. 2. Piperazines, Bicyclic Amines, Bridged Bicyclic Amines, and Miscellaneous Compounds”; Journal of Medicinal Chemical Society, vol. 36, 1993, 2311-2320.
PCT International Search Report.

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