3-aminopiperidine derivatives and related nitrogen containing he

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546176, 546193, 546199, 546208, 546209, 546210, 546212, 546213, 546214, 546216, 546218, 546223, 546224, C07D21176

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053328175

ABSTRACT:
The present invention relates to novel 3-amino-piperidine derivatives and related nitrogen containing heterocyclic compounds, and specifically, to compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, Y and m are as defined below. These novel compounds are useful in the treatment of inflammatory and central nervous system disorders, as well as other disorders. The invention also relates to novel intermediates used in the synthesis of compounds of the formula I.

REFERENCES:
patent: 3560510 (1971-02-01), Warawa
patent: 3992389 (1976-11-01), Cavalla et al.
patent: 4785119 (1988-11-01), Hojo et al.
Muehlstaedt et al., Chemical Abstracts, vol. 84 (1976) 89768m.
Journal Fur Praktische Chemie, 317(6), 919-925 (1975).
Desai et al., J. Med. Chem., 35, 4911-4913 (1992).

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