3-Aminomethylene-2,4-pentanedione bis(thiosemicarbazone) derivat

Details 3-Aminomethylene-2,4-pentanedione bis(thiosemicarbazone) derivat 3-Aminomethylene-2,4-pentanedione bis(thiosemicarbazone) derivat

1983-06-30

1986-01-14

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260112R, 2601125R, 260121, 424 11, 435188, 435215, 562556, C07G 704, C07G 700

Patent

active

045644721

ABSTRACT:
A radioactive diagnostic agent which comprises a physiologically active substance and a radioactive metallic element combined with a compound of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are each hydrogen, C.sub.1 -C.sub.3 alkyl or phenyl. The agent is characteristic in having a high stability even after being administered into a human body and showing the substantially the same behavior as the physiologically active substance itself in a human body.

REFERENCES:
patent: 3382275 (1968-05-01), Barrett
patent: 3709935 (1973-01-01), Barrett
patent: 3824276 (1974-07-01), Murray et al.
patent: 4287362 (1981-09-01), Yokoyama et al.
patent: 4338248 (1982-07-01), Yokoyama et al.
Polonovski et al., Comptes Rend. 232, 1260-1262, 1951.
J. of Nucl. Med., vol. 17, No. 9, 816-819, (1976), Yokoyama et al.
Yakugaku Zasshi, 97, pp. 671-675, (1977), Nishimura et al.

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