3-Aminomethylene-2,4-pentanedione bis(thiosemicarbazone) derivat

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260112R, 2601125R, 260121, 424 11, 435188, 435215, 562556, C07G 704, C07G 700

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active

045644721

ABSTRACT:
A radioactive diagnostic agent which comprises a physiologically active substance and a radioactive metallic element combined with a compound of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are each hydrogen, C.sub.1 -C.sub.3 alkyl or phenyl. The agent is characteristic in having a high stability even after being administered into a human body and showing the substantially the same behavior as the physiologically active substance itself in a human body.

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Polonovski et al., Comptes Rend. 232, 1260-1262, 1951.
J. of Nucl. Med., vol. 17, No. 9, 816-819, (1976), Yokoyama et al.
Yakugaku Zasshi, 97, pp. 671-675, (1977), Nishimura et al.

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