3-aminocarbonylmethoxy-5-phenylpyrazole compounds, antiarrythmic

Details 3-aminocarbonylmethoxy-5-phenylpyrazole compounds, antiarrythmic 3-aminocarbonylmethoxy-5-phenylpyrazole compounds, antiarrythmic

1985-07-02

1987-09-22

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514326, 514407, 544140, 546211, 548369, 548374, 548375, A61K 31415, A61K 31535, C07D23120, C07D40512

Patent

active

046955666

ABSTRACT:
3-(aminoalkylaminocarbonylmethoxy)-5-phenylpyrazole compounds corresponding to the formula: ##STR1## in which R.sub.1, R.sub.2, R.sub.5, R.sub.6, R.sub.7, and R.sub.8 and R.sub.9 may be hydrogen or lower alkyl groups, or R.sub.5 with R.sub.6 and/or R.sub.8 with R.sub.9 may also form specified cyclic groups, R.sub.3 and R.sub.4 may be hydrogen, halogen, lower alkyl, lower alkoxy, trifluoromethyl, nitro, hydroxy or alkylene dioxy, and Z represents an alkylene chain or the 2-hydroxypropylene chain. The compounds possess pharmacological, in particular antiarrhythmic, properties.

REFERENCES:
patent: 3962453 (1976-06-01), Ahrens et al.

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