3-aminoazetidine, its salts, process for their preparation and i

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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548473, C07D20504

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active

049436414

ABSTRACT:
The 3-aminoazetidine, its salts, new intermediates of formula ##STR1## wherein X' represents hydrogen or a protecting group and both X" represent hydrogen or, together with the nitrogen atom, a phthalimido group, X' and both X" not being hydrogen at the same time; a process for the preparation of the 3-aminoazetidine, starting from a 1-protected 3-sulfonyloxyazetidine by reaction with the potassium phthalimide and transformation of the above mentioned intermediates.

REFERENCES:
patent: 4533673 (1985-08-01), Nakane
Nisato et al., "Synthese de l'amino-3 azetidine", J. Heterocyclic Chem. 22, 961 (1985).
Colombo et al., "Liquid-Phase Synthesis of Naturally Occurring Peptides" Hoppe-Seyler's Z. Physiol. Chem., 1981 (362(10) 1385-91.
Roberts et al., Basic Principles of Organic Chemistry, pp. 552-554, 1965.

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