3-aminoazetidine, its salts and intermediates of synthesis

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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548473, C07D20504

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active

048228958

ABSTRACT:
The 3-aminoazetidine, its salts, new intermediates of formula ##STR1## wherein X' represents hydrogen or a protecting group and both X" represent hydrogen or, together with the nitrogen atom, a phthalimido group, X' not and both X" being hydrogen at the same time; a process for the preparation of the 3-aminoazetidine, starting from a 1-protected 3-sulfonyloxyazetidine by reaction with the potassium phthalimide and transformation of the above mentioned intermediates.

REFERENCES:
patent: 3929765 (1975-12-01), Suzuki et al.
Gaertner, J. Org. Chem., vol. 35 (11), (1970) p. 3952.
Hasegawa, et al., Chem. Abstracts, vol. 78, (1973), entry 147770v.
Chen, et al., Chem. Abstracts, vol. 77, (1972), entry 34212a.
Cromwell, et al., Chem. Reviews, 79(4), (1979), pp. 331, 344 and 345.
Chen et al., "Azetidines IV. The Reaction of 1-t-Butylazitidinyl-3 Tosylate with Amines and Mercaptans", Bulletin of the Chemical Society of Japan, vol. 41, pp. 712-716 (1968).
Chem. Abstracts 83: 9760u Jul. 7, 1975.

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