3-Amino-6-substituted thio-1-azabicyclo(3.2.0)hept-6-en-2-one-7-

Details 3-Amino-6-substituted thio-1-azabicyclo(3.2.0)hept-6-en-2-one-7- 3-Amino-6-substituted thio-1-azabicyclo(3.2.0)hept-6-en-2-one-7-

1982-04-19

1984-01-31

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

2602452R, 424244, 424263, 424272, 424250, 424251, 424273R, 424270, 548515, C07D20512, A61K 31395

Patent

active

044289600

ABSTRACT:
Disclosed are 3-amido-6-substituted thio-1-azabicyclo[3.2.0]hept-6-en-2-one-7-carboxylic acids (I) and their pharmaceutically acceptable salts and esters which are useful as antibiotics ##STR1## wherein: R is NH.sub.2, R.sup.1 NH, R.sup.1 is acyl; and R.sup.8 is inter alia, unsubstituted and substituted alkyl, alkenyl, aryl, and aralkyl.
Also disclosed are processes for the preparation of such compounds; pharmaceutical compositions comprising such compounds; and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.

REFERENCES:
patent: 4372965 (1983-02-01), Christensen et al.

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