3-amino-5-o-chlorobenzyl-4,5,6,7-tetrahy drothieno[3,2-c]-pyridi

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D33350

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052966038

ABSTRACT:
Intermediates of the following formulae (I) and (II): ##STR1## wherein R.sup.1 represents a hydrogen atom or an alkyl group ##STR2## wherein R.sup.1 represents a hydrogen atom or an alkyl group, and R.sup.2 represents a hydrogen atom, an alkylcarbonyl group, arylcarbonyl group, alkylsulfonyl group, arylsulfonyl group, alkoxycarbonyl group or aryloxycarbonyl group
and acid salt thereof are useful for synthesizing ticlopidine hydrochloride from an inexpensive and easily available compound in short steps.

REFERENCES:
patent: 4051141 (1977-09-01), Castaigne
patent: 4127580 (1978-11-01), Braye
Bulletin de la Societe Chimique de France, Part II, No. 1-2, 1978, pp. II-48 to II-54.
Chemical Abstracts, vol. 109, No. 13, Sep. 26, 1988, Columbus, Ohio, Abstract No. 110409s.
Chemical Abstracts, vol. 83, No. 23, Dec. 8, 1975, Columbus, Ohio, Abstract No. 193276q.
Chemical Abstracts, vol. 79, No. 11, Sep. 17, 1973, Columbus, Ohio, Abstract No. 66340y.
Chemical Abstracts, vol. 89, No. 19, Abstract 163,455d, p. 565, Nov. 6, 1978, Maffrand et al.
Dunn et al, J. of Heterocyclic Chemistry, vol. 24, No. 1, pp. 85-89, 1987.

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