(3-amino-1H-pyrazol-4-yl) (aryl)methanones

Details (3-amino-1H-pyrazol-4-yl) (aryl)methanones (3-amino-1H-pyrazol-4-yl) (aryl)methanones

1984-05-24

1990-02-13

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548362, C07D40106, C07D40506

Patent

active

049008366

ABSTRACT:
(3-Amino-1H-pyrazol-4-yl)(aryl)methanones which are new compounds having utility as intermediates for the preparation of aryl and heteroaryl[7-(aryl and heteroaryl)pyrazolo[1,5-a]pyrimidin-3-yl]methanones, which are therapeutic agents.

REFERENCES:
patent: 3660425 (1972-05-01), De Wald et al.
Butler, Donald E. and DeWald, Horace A., "New General Methods For The Substitution of 5-Chloropyrazoles. The Syntheses of 1,3-Dialkyl-2-pyrazolin-5-ones", J. Org. Chem. 1971, 36:2542-2547.
Butler, Donald E., Wise, Lawrence D. and DeWald, Horace A., "(1,3-Dialkyl-5-amino-1H-pyrazol-4-yl)aryl-methanones. A series of Novel Central Nervous System Depressants", J. Med. Chem. 1984, 27:1396-1400.

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