3-Amino-1-phenyl-2-pyrazolines

Details 3-Amino-1-phenyl-2-pyrazolines 3-Amino-1-phenyl-2-pyrazolines

1984-05-23

1986-01-14

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548379, A61K 31415, C07D23106

Patent

active

045646848

ABSTRACT:
Heterocyclic compounds of formula (I) and acid addition salts thereof inhibit arachidonic acid oxygenation and are useful in medicine, for example as anti-inflammatory agents. ##STR1## The compounds of formula (I) may be prepared by any method analogous to those known in the art, for example by the method of G. F. Duffin and J. D. Kendall in J. Chem. Soc. (1954), 408-415. When used in medicine, the compounds of formula (I) may be administered as the compound alone or as a pharmaceutical formulation together with a pharmaceutically acceptable carrier.

REFERENCES:
patent: 2726248 (1955-12-01), Kendall et al.
patent: 4149005 (1979-04-01), Battisti et al.
Elguero et al. I, Bull. Soc. Chim. France 1970, No. 4, pp. 1576-1581.
Elguero et al. II, Bull. Soc. Chim. France 1969, No. 5, pp. 1683-1686.
Higgs et al., Chem. Abst. 1980, vol. 92, No. 15404h.
Duffin et al., J. Chem. Soc. 1954, pp. 408-415.

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