3-Amino-[1]-benzazepin-2-one-1-alkanoic acids

Details 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids

1982-07-19

1983-10-18

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2602393B, 2602393T, C07D22316, A61K 3155

Patent

active

044105207

ABSTRACT:
Variously substituted 1-carboxymethyl-3-(carboxymethylamino)-2,3,4,5-tetrahydro-1H-[1]benzazepin -2-ones and functional derivatives are angiotension converting enzyme inhibitors and are useful as antihypertensive agents. Synthesis of, compositions and methods of treatment utilizing such compounds are included.

REFERENCES:
patent: 3748321 (1973-07-01), Krapcho
Stewart, "Australian J. of Chemistry", vol. 33 (1980), pp. 633-640.
Friedinger et al., "J. Org. Chem.", vol. 47, pp. 104-109 (1982).
Australian J. Chem., vol. 33, 633 (1980).
Japan 74-028753, 7/29/1974, CA 82, 139978m (1975).
Japn 74-028754, 7/29/1974, CA 82, 139981g (1975).
Paquette et al., J. Organic Chemistry, vol. 34, pp. 2879-2880, (1969).
Smith et al., J. Medicinal Chemistry, vol. 24, pp. 104-109, (1981).
Patchett et al., Nature, vol. 288, pp. 280-283, (1980).
J. Org. Chem., vol. 34, 2879 (1969).
J. Med. Chem., vol. 24, 104 (1981).
Nature, vol. 288, 280 (1980).

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