3-amidochromanylsulfonyl(thio)ureas, processes for their prepara

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514183, 514212, 514320, 514414, 514422, 514456, 540463, 540524, 546141, 546196, 548454, 548525, 549404, C07D31158, C07D40512, A61K 3135

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058497552

ABSTRACT:
3-amidochromanylsulfonyl(thio)ureas of the formula (I): ##STR1## which are valuable pharmaceutically active compounds for the treatment of disturbances of the cardiovascular system, in particular for the treatment of arrhythmias, for preventing sudden cardiac death or for influencing a reduced contractility of the heart, and processes for their preparation, their use and pharmaceutical preparations comprising them.

REFERENCES:
patent: 5574069 (1996-11-01), Englert et al.
patent: 5652268 (1997-07-01), Englert et al.
P. Smits et al.; "Cardiovascular Effects of Sulphonylurea Derivatives Implications for the Treatment of NIDDM", Diabetologia, vol. 38, pp. 116-121, Jan. 1, 1995.

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