3-Amido-1,2,3,4-tetrahydrocarbazoles

Details 3-Amido-1,2,3,4-tetrahydrocarbazoles 3-Amido-1,2,3,4-tetrahydrocarbazoles

1973-12-17

1976-05-25

Winters, Sherman D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602475FP, 26029361, 424267, 424274, C07D20988

Patent

active

039593096

ABSTRACT:
3-(Substituted-amino)-1,2,3,4-tetrahydrocarbazoles are prepared by reacting appropriate 4-substituted-aminocyclohexanones with a phenylhydrazine, by reacting a 3-(sulfonyloxy)-1,2,3,4-tetrahydrocarbazole with an appropriate substituted amine, or by reduction of an appropriate 3-(acylamino)-1,2,3,4-tetrahydrocarbazole. The 3-(substituted-amino)-1,2,3,4-tetrahydrocarbazoles of this invention have analgetic and psychotropic activities. Moreover, certain of these compounds also have antihistaminic activity.

REFERENCES:
patent: 3592824 (1971-07-01), Schut
patent: 3634420 (1972-01-01), Littell et al.
patent: 3642816 (1972-02-01), Mooradian
J. Pharmacol. Expt'l. Therap. 99: 450-457 (1950), Eagle et al.
Can. J. Chem. 42: 1940-1947 (1964), Robinson et al.
Chemical Abstracts 57: 9782e (1962), Murthy et al.

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