(3-Alkylamino-2-hydroxypropoxy)-furan-2-carboxylic acid anilides

Details (3-Alkylamino-2-hydroxypropoxy)-furan-2-carboxylic acid anilides (3-Alkylamino-2-hydroxypropoxy)-furan-2-carboxylic acid anilides

1980-06-03

1981-05-26

Raymond, Richard

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

Bacterium or component thereof or substance produced by said...

2603473, 542406, 542421, C07D30754, C07D30773

Patent

active

042698553

ABSTRACT:
(3-Alkylamino-2-hydroxypropoxy)-furan-2-carboxylic acid anilides of the formula: ##STR1## in which R.sub.1 denotes a straight or branched C.sub.1 to C.sub.5 alkyl group or a cyclopropyl or cyclopentyl group, R.sub.2 denotes a hydrogen or halogen atom or a methyl, methoxy, nitro or acetyl group, R.sub.3 denotes a hydrogen or halogen atom or a nitro group and A denotes a single bond or the --CH.sub.2 -- or --CH.dbd.CH-- group, and physiologically tolerated acid addition salts thereof possess .beta.-adrenolytic properties and a low toxicity.

REFERENCES:
patent: 3959481 (1976-05-01), Davis et al.
patent: 4013684 (1977-03-01), Merkle et al.
patent: 4187237 (1980-02-01), Deinhammer et al.

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