3-Alkoxy-thianapthene-2-carboxamides

Details 3-Alkoxy-thianapthene-2-carboxamides 3-Alkoxy-thianapthene-2-carboxamides

1974-06-26

1976-05-04

Weinberger, Lorraine A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260268BC, 26029357, 2603097, 26032635, 2603305, 424248, 424250, 424267, 424274, 424275, C07D33370

Patent

active

039547485

ABSTRACT:
The 3-alkoxy-thianaphthene-2-carboxamides of this invention are effective for the treatment of mammals afflicted with emesis. When administered to dogs in dosages of 250 .mu.g/kg, compounds of this invention give 100% protection against vomiting normally induced by subcutaneous administration of apomorphine. The compounds of this invention also favorably modify behavior disturbances in mammals.

REFERENCES:
patent: 2876235 (1959-03-01), Voegtli
patent: 3622574 (1971-11-01), Wright et al.
patent: 3651094 (1972-02-01), Libis et al.
Campaigne et al.; Chem. Abst. 68: 68811z, (1968).

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