3-alkoxy substituted benzofuro[3,2-c]quinolin-6-one compounds

Details 3-alkoxy substituted benzofuro[3,2-c]quinolin-6-one compounds 3-alkoxy substituted benzofuro[3,2-c]quinolin-6-one compounds

1989-11-22

1991-12-17

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514285, 544125, 546 62, A61K 31535, C07D41300

Patent

active

050735535

ABSTRACT:
Benzofuro[3,2-c]quinoline compounds of the formula: ##STR1## wherein A represents a group of the formula of --CH.sub.2) .sub.m or --CH.sub.2 CH(OH)CH.sub.2 --; Y represents an N,N-di-alkylamino group, an N-mono-alkylamino group or a nitrogen atom-containing aliphatic geterocyclic group; n represents 0 or 1; m represents an integer of from 1 to 3, and pharmaceutically acceptable acid addition salts thereof, possess a strong inhibitory action on bone resorption, a stimulatory effect on ossification.

REFERENCES:
patent: 5023261 (1991-06-01), Kamijo et al.
Advanced Tissue Cultures for In Vitro Assay and Production, pp. 103-115 (1985), Edited by Isao Yamane & Hiroyoshi Endo.
El-Manah et al., "Potent. Non-Ster. Estrogen and Anti Estrog. Synthesis", Croatica Chemica Acta, 59(1), 171-6 (1986).
Yamaguchi et al., "Synth. Benzofuroquinolines", Hetocyclic Chem., 21, pp. 737-739 (1984).

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