3-Acyloxymethyl-cephem compounds

Details 3-Acyloxymethyl-cephem compounds 3-Acyloxymethyl-cephem compounds

1978-04-17

1979-08-28

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544 22, 544 30, 424246, C07D50120, A61K 31545

Patent

active

041661788

ABSTRACT:
Novel 3-acyloxymethyl-cephem compounds of the formula: ##STR1## wherein R.sup.1 is hydrogen or an acyl group; X is a divalent group consisting of a carbon chain having 2 to 3 carbon atoms and a carbonyl or sulfonyl group at one terminal end thereof, said divalent group being either substituted or unsubstituted on the carbon chain; and Z is an organic acid residue, and salts thereof were found to be useful as starting materials for preparing cephalosporins of the formula: ##STR2## wherein R.sup.2 stands for a residue of a nucleophilic compound and R.sup.1 has the same meaning as above.

REFERENCES:
patent: 3941774 (1976-03-01), Clayton et al.

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