3-acetoxymethyl-7-(iminoacetamino)-cephalosporanic acid derivati

Details 3-acetoxymethyl-7-(iminoacetamino)-cephalosporanic acid derivati 3-acetoxymethyl-7-(iminoacetamino)-cephalosporanic acid derivati

1990-09-13

1992-04-07

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D277593

Patent

active

051030128

ABSTRACT:
Compounds of the formula ##STR1## wherein R is selected from the group consisting of hydrogen and groups easily removable by acid hydrolysis or hydrogenolysis, R' is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms, alkenyl and alkynyl of 2 to 4 carbon atoms and groups easily removable by acid hydrolysis or hydrogenolysis, A is selected from the group consisting of hydrogen, alkali metal and equivalents of an alkaline earth metal or magnesium and an organic amine base with the proviso that when R' is a group easily removable by acid hydrolysis or hydrogenolysis, R is also and when R' is hydrogen, R also is hydrogen and the wavy line means the OR' group may be in either one of the two possible syn or anti positions having antibiotic activity and process for their preparation.

REFERENCES:
patent: 4166115 (1979-08-01), Takaya
patent: 4203899 (1980-05-01), Ochiai
patent: 4278671 (1981-07-01), Ochiai
patent: 4376203 (1983-03-01), Heymes

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