3,8-Dioxo-scirpen-4.beta.,15-diol esters and their use as antitu

Details 3,8-Dioxo-scirpen-4.beta.,15-diol esters and their use as antitu 3,8-Dioxo-scirpen-4.beta.,15-diol esters and their use as antitu

1979-07-27

1981-01-13

Chan, Nicky

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424283, C07D31178

Patent

active

042448743

ABSTRACT:
A novel series of 3,8-dioxo-scirpen-4.beta.,15-diol esters is provided for use as antitumor agents. Also provided are various novel intermediates used in the production of such compounds.

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Murphy et al., Proc. Amer. Assoc. Cancer Res., 17, 90 (1976).
Haas et al., ibid., 18, 296 (1977).
Pathre et al., J. Agric. Food Chem., 24, 97 (1976).
Tatsuno et al., J. Pure and Applied Chem., 35, 309 (1973).
Grove, J. Chem. Soc. (C), 375 (1970).
Grove et al., Biochemical Pharmacology, 24, 959 (1972..
Wei et al., Biochem. and Biophys. Res. Comm., 57, 838 (1965).
Sigg et al., Helv. Chim. Acta, 48, 962 (1965).

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