3,7-Inter-m-phenylene-3-oxa-4,5,6-trinor-13,14-didehydro-11-deox

Details 3,7-Inter-m-phenylene-3-oxa-4,5,6-trinor-13,14-didehydro-11-deox 3,7-Inter-m-phenylene-3-oxa-4,5,6-trinor-13,14-didehydro-11-deox

1977-08-01

1978-09-12

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 62, 560 63, 562468, C07C17700

Patent

active

041139666

ABSTRACT:
This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is replaced by a triple bond. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.

REFERENCES:
derwent Abstract 47234-B DT 2305044-Q (09/08/73).
Derwent Abstract 18176Y/11 BE 846-080 (10/03/77).
Derwent Abstract 61891X/32 DT 2603-172 (05/08/76).
Derwent Abstract 59715X/32 BE 839-533 (01/07/76).
Derwent Abstract 79219X/42 US 3,984,400 (05/01/76).

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