Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1977-08-01
1978-10-17
Killos, Paul J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
560 51, 562463, 562464, C07C17700
Patent
active
041210387
ABSTRACT:
This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is replaced by a triple bond. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
REFERENCES:
derwent Abstract, 47234-B, DT 2305044-Q, (09/08/73).
Derwent Abstract, 18176Y/11, BE 846-080, (10/03/77).
Derwent Abstract, 61891X/33, DT 2603-172, (05/08/76).
Derwent Abstract, 59715X/32, BE 839-533, (01/07/76).
Derwent Abstract, 79219X/42, U.S. 3984,400, (05/10/76).
Armitage Robert A.
Killos Paul J.
The Upjohn Company
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