3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds

Details 3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds 3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds

1982-02-26

1983-08-16

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

424246, 544 16, C07D50118

Patent

active

043992781

ABSTRACT:
7-Amino-2 or 3-cephem-4-carboxylic acid compounds of the formula: ##STR1## wherein R.sup.1 is amino; R.sup.2 is carboxy or carboxy protected by a pharmaceutically acceptable group; ##STR2## is di(lower)alkylamino(lower)alkylamino, an unsaturated or saturated 3 to 8 membered heteromonocyclic(lower)alkylamino group containing 1 to 4 nitrogen atoms, an unsaturated or saturated 3 to 8 membered heteromonocyclic(lower)alkylamino group containing 1 to 4 nitrogen atoms substituted by lower alkyl orhydroxy(lower)alkyl, an unsaturated or saturated 5 to 6 membered heteromonocyclic group containing 2 to 4 nitrogen atoms, an unsaturated or saturated 5 to 6 membered heteromonocyclic group containing 2 to 4 nitrogen atoms substituted by lower alkyl or hydroxy(lower)alkyl or hydroxypiperidino, and X is --S or ##STR3## and pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 4224441 (1980-09-01), Tsushima et al.
patent: 4252974 (1981-02-01), Laing et al.
patent: 4292427 (1981-09-01), Marburg et al.
patent: 4327093 (1982-04-01), Ueda et al.

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