3,7-dihydro-purine-2,6-dione derivatives as CRF receptor...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S263350, C514S263360, C514S263220

Reexamination Certificate

active

07098217

ABSTRACT:
3,7-Dihydro-purine-2,6-dione derivatives of Formula (I) are providedwherein R1, R2, R3and R4are herein defined for use as CRF receptor ligands in the treatment of disorders characterized by overexpression of corticotropin releasing factor (CRF), such as anxiety, depression, and irritable bowel syndrome.

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