3,6-substituted imidazol[1,2-b]pyridazine analogs for...

Details 3,6-substituted imidazol[1,2-b]pyridazine analogs for... 3,6-substituted imidazol[1,2-b]pyridazine analogs for...

2011-03-15

2011-03-15

Padmanabhan, Sreeni (Department: 1627)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S252060, C514S393000, C544S236000, C544S238000, C548S303100

Reexamination Certificate

active

07906512

ABSTRACT:
Methods for treating an allergic or inflammatory disease or other Syk-mediated disease or Syk-mediated condition characterized by administering a composition which contains a therapeutically effective amount of a 3,6-substituted imidazol[1,2-b]pyridazine compound.

REFERENCES:
patent: 2004/0067948 (2004-04-01), Hallett
patent: WO2004014382 (2004-02-01), None
patent: WO2004085409 (2004-10-01), None
Charles L. Cywin, et al., Discovery and SAR of Novel [1,6]Naphthyridines as Potent Inhibitors of Spleen Tyrosine Kinase (SYK), Biorganic & Medicinal Chemistry Letters, 2003, pp. 1415-1418, vol. 13.
Justine Y. Q. Lai, et al., “Potent Small Molecule Inhibitors of Spleen Tyrosine Kinase (Syk),” Biorganic & Medicinal Chemistry Letters, 2003, pp. 3111-3114, vol. 13.
Reuben P. Siraganian, et al., “Protein Tyrosine Kinase Syk in Mast Cell Signaling,” Molecular Immunology, 2001, pp. 1229-1233, vol. 38.
Jennifer A. Taylor, et al., “Activation of the High-Affinity Immunoglobulin E Receptor FcεRI in RBL-2H3 Cells is Inhibited by Syk SH2 Domains,” Molecular and Cellular Biology, 1995, pp. 4149-4157, vol. 15, No. 8.
Noriyuki Yamamoto, et al., “The Orally Available Spleen Tyrosine Kinase Inhibitor 2-[7-(3,4-Dimethoxyphenyl)-imidazo[1,2-c]pyrimidin-5-ylamino]-nicotinamide Dihydrochloride (BAY 61-3606) Blocks Antigen-Induced Airway Inflammation in Rodents,” The Journal of Pharmacology and Experimental Therapeutics, 2003, pp. 1174-1181, vol. 306, No. 3.

Affiliated with

Also associated with

Rating

3,6-substituted imidazol[1,2-b]pyridazine analogs for... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3,6-substituted imidazol[1,2-b]pyridazine analogs for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3,6-substituted imidazol[1,2-b]pyridazine analogs for... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2630753