3,6-ketal and enol ether macrolide antibiotics

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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Details

536 72, 536 74, 536 185, A61K 3170, C07H 1708

Patent

active

060432268

ABSTRACT:
This invention relates to compounds of formulas 1 and 2 ##STR1## and to pharmaceutically acceptable salts and solvates thereof, wherein X, X.sup.1, R.sup.1, R.sup.2, R.sup.7, R.sup.17 and R.sup.19 are as defined herein. The compounds of formulas 1 and 2 may be useful in the treatment of bacterial, parasitic and protozoal infections, as well as disorders related to bacterial, parasitic and protozoal infections, in mammals, fish and birds. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and 2 and to methods of treating bacterial, parasitic and protozoal infections by administering the compounds of formula 1 and 2.

REFERENCES:
patent: 4957905 (1990-09-01), Hunt

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