3,6-disubstituted triazolo [3,4-A]phthalazine derivatives

Details 3,6-disubstituted triazolo [3,4-A]phthalazine derivatives 3,6-disubstituted triazolo [3,4-A]phthalazine derivatives

1984-07-11

1988-11-08

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544234, 544115, 514212, 514218, 5142332, 540553, 540575, 540599, A61K 3150, A61K 3155, C07D48704

Patent

active

047834617

ABSTRACT:
The present invention is directed to new 3,6-disubstituted-1,2,4-triazolo[3,4-a]phthalazine derivatives of formula I ##STR1## wherein R represents phenyl or substituted phenyl, n is 1 or 2, R.sup.1 is an amino group of formula NR.sup.4 R.sup.5, or an alkoxy of cycloalkoxy group of formula OR.sup.6, and R.sup.2 and R.sup.3 represent hydrogen, halogen, (C.sub.1 -C.sub.4)alkyl or (C.sub.1 -C.sub.4)alkoxy, to the process for their preparation and to the pharmaceutical compositions containing them. The compounds of the present invention are as active as anti-anxiety substances.

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