3,6-Bicyclolides

Details 3,6-Bicyclolides 3,6-Bicyclolides

2007-06-12

2007-06-12

Peselev, Elli (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S007200, C536S007300, C536S007400

Reexamination Certificate

active

11008581

ABSTRACT:
The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof:which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

REFERENCES:
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patent: 6075011 (2000-06-01), Or et al.
patent: 6734292 (2004-05-01), Omura et al.
patent: 0 559 896 (1991-11-01), None
patent: WO 93/21200 (1993-10-01), None
patent: WO 97/10251 (1997-03-01), None
patent: WO 00/78773 (2000-12-01), None
patent: WO 03/095466 (2003-11-01), None
patent: WO 03/097659 (2003-11-01), None
Zhenkun, Ma, et al., “Novel Erythromycin Derivatives With Aryl Groups Tethered to the C-6 Position are Potent Protein Synthesis Inhibitors and Active Against Multidrug-Resistant Respiratory Pathogens,”J. Med. Chem., 44: 4137-4156 (2001).

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