3,5-ditertiarybutyl-4-hydroxyphenyl, 1,3,4-thiadiazoles and oxad

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548136, 548141, 548142, 548143, 548144, C07D271113, A61K 3141

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active

051028972

ABSTRACT:
The novel 3,5-ditertiarybutyl-4-hydroxyphenylthio-1,3,4-thiadiazoles and oxadiazoles and 3,5-ditertiarybutyl-4-hydroxyphenylmethanone-1,3,4-thiadiazoles and oxadiazoles and related compounds of the present invention are antiinflammatory agents having activity as inhibitors of 5-lipoxygenase, cyclooxygenase or both.

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Derwent Abstr. No. 70909y/40.

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