3,5-diamino-1,2,4-triazole derivatives

Details 3,5-diamino-1,2,4-triazole derivatives 3,5-diamino-1,2,4-triazole derivatives

1990-01-23

1991-07-02

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D24908

Patent

active

050287168

ABSTRACT:
A triazole derivative represented by the formula ##STR1## wherein R.sup.1 is a hydrogen atom, a lower alkyl group having 1 to 4 carbon atoms, an acetyl group, a naphthylmethyl group, an anthrylmethyl group or a group of the formula ##STR2## wherein X, Y and Z are the same or different and each a hydrogen atom, a halogen atom, a lower alkyl group having 1 to 4 carbon atoms, a lower alkoxy group having 1 to 4 carbon atoms, a hydroxyl group, a nitro group, a trifluoromethyl group, a cyano group or a benzyloxy group, and R.sup.2 is a hydrogen atom or an acetyl group, and R.sup.3 is a hydrogen atom, an acetyl group or a group of the formula ##STR3## wherein R.sup.1 and R.sup.2 are as defined above, are useful as the inhibitors of lipid peroxidation.

REFERENCES:
Chemical Abstracts, vol. 108, No. 7, Feb. 15, 1988, p. 718, Col. 2, Ab. No. 55990b.
Chemical Abstracts, vol. 104, No. 19, May 12, 1986, p. 673, Col. 2, Ab. No. 168468y.
Chemical Abstracts, vol. 98, No. 3, Jan. 17, 1983, p. 15, Col. 1, Ab. No. 11101h.

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