Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1986-06-16
1988-09-20
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514252, 514253, 514256, 514257, 514318, 514320, 514326, 514333, 514334, 514341, 514362, 514363, 5142278, 5142362, 544 60, 544 62, 544111, 544114, 544122, 544132, 544295, 544333, 544357, 544360, 544367, 544376, 544405, 546193, 546196, 546277, 546283, 546405, 548127, 548128, 548131, 548133, A61K 3141, A61K 31535, C07D27106, C07D41302
Patent
active
047726229
ABSTRACT:
Novel diamino oxadiazoles, wherein one of the amine functions is connected to a basicly-substituted heterocyclic group through a linear or cyclic connecting group, which are useful for the suppression of gastric acid secretions in mammals. Compositions employing these compounds and processes for the preparation of such compounds from known N-cyano-S-methylisothiourea precursors by treatment with hydroxylamine and for alkylation of amine groups are also disclosed.
REFERENCES:
patent: 3574222 (1971-04-01), Eloy et al.
patent: 3950333 (1976-04-01), Durant et al.
patent: 4089966 (1978-05-01), Cohen
patent: 4128658 (1978-05-01), Price et al.
patent: 4394508 (1983-07-01), Crenshaw
Britcher Susan F.
Lumma, Jr. William C.
Daus Donald G.
Merck & Co. , Inc.
Meredith R. D.
Pfeiffer H. J.
Shen Cecilia
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