3,5-di-tertiary-butyl-4-hydroxyphenyl thiazolyl, oxazolyl, and i

Details 3,5-di-tertiary-butyl-4-hydroxyphenyl thiazolyl, oxazolyl, and i 3,5-di-tertiary-butyl-4-hydroxyphenyl thiazolyl, oxazolyl, and i

1991-01-31

1992-02-04

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514372, 518200, 518201, 518214, 518236, 518248, 518343, 518378, C07D27724, C07D27502, A61K 31425

Patent

active

050860640

ABSTRACT:
The novel 3,5-di-tertiary-butyl-4-hydroxyphenylthiazolyl, -oxazolyl, or -imidazolyl methanones and methanone oximes of the present invention are antiinflammatory agents having activity as inhibitors of 5-lipoxygenase, cyclooxygenase or both.

REFERENCES:
patent: 4535165 (1985-08-01), Moore
Mar., Advanced Organic Chemistry, pp. 484-486, (1985).

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