3,5-di-tertiary-butyl-4-hydroxyphenyl imidazolyl methanones and

Details 3,5-di-tertiary-butyl-4-hydroxyphenyl imidazolyl methanones and 3,5-di-tertiary-butyl-4-hydroxyphenyl imidazolyl methanones and

1991-10-17

1993-08-10

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5483335, 5483741, 5483345, 514400, 514 4, C07D23110, C07D23364, A61K 31415

Patent

active

052349390

ABSTRACT:
The novel 3,5-di-tertiary-butyl 4-hydroxyphenylimidazolyl methanones and methanone oximes of the present invention are antiinflammatory agents having activity as inhibitors of 5-lipoxygenase, cyclooxygenase or both.

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patent: 4810716 (1989-03-01), Connor
patent: 5086064 (1992-02-01), Capiris
patent: 5102897 (1992-04-01), Boschelli
Milaev, Zh Obshch Khim, 50, (2) 473 (1980).
EPO 91 104 797 (corresponding) Search Report.
Derwent Abstract No. 88-326016/46 (J63239-273-A).
Derwent Abstract No. 87-285927/41 (EP 241-043-A).
Derwent Abstract No. 83-786513/41 (J58148-858-A).
Derwent Abstract No. 19743 D/12 (EP 24-829).
Derwent Abstract No. 88-199352/29 (EP 274-867-A).

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