Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-08-23
1992-10-13
Gerstl, Robert
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514361, 548128, 548129, 548136, 548138, 548139, 548140, C07D28508, C07D28512, A61K 3141
Patent
active
051551225
ABSTRACT:
The present invention is novel compounds which are 3,5-di-tertiary-butyl-4-hydroxyphenyl substituted 1,2,4- and 1,3,4-thiadazoles and oxadiazoles, and 1,2,4-triazoles, and pharmaceutically acceptable additions and base salts thereof, pharmaceutical compositions and methods of use therefor. The invention compounds are now found to have activity as inhibitors of 5-lipoxygenase and/or cyclooxygenase providing treatment of conditions advantageously affected by such inhibition including inflammation, arthritis, pain, fever, and the like.
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Derwent Abstract No. 86-051943/08 Referring to Japanese Application No. J61500-072-A.
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Connor David T.
Flynn Daniel L.
Kostlan Catherine R.
Mullican Michael D.
Shrum Gary P.
Daignault Ronald A.
Gerstl Robert
Thierstein Joan
Warner-Lambert & Company
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