Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-06-29
1993-10-26
Gerstl, Robert
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548131, 548132, 548133, C07D27110, C07D 27113, A61K 3141
Patent
active
052566803
ABSTRACT:
The present invention is novel compounds which are 3,5-di-tertiary-butyl-4-hydroxyphenyl substituted 1,2,4- and 1,3,4-thiadazoles and oxadiazoles, and 1,2,4-triazoles, and pharmaceutically acceptable additions and base salts thereof, pharmaceutical compositions and methods of use therefor. The invention compounds are now found to have activity as inhibitors of 5-lipoxygenase and/or cyclooxygenase providing treatment of conditions advantageously affected by such inhibition including inflammation, arthritis, pain, fever, and the like.
REFERENCES:
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Connor David T.
Flynn Daniel L.
Kostlan Catherine R.
Mullican Michael D.
Shrum Gary P.
Daignault Ronald A.
Gerstl Robert
Thierstein Joan
Warner-Lambert & Company
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