3-[5-(2-fluoro-phenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid,...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S125000, C548S131000, C514S361000

Reexamination Certificate

active

07419991

ABSTRACT:
Novel 1,2,4-oxadiazole benzoic acid compounds, methods of using and pharmaceutical compositions comprising an 1,2,4-oxadiazole benzoic acid derivative are disclosed. The methods include methods of treating or preventing a disease ameliorated by modulation of premature translation termination or nonsense-mediated mRNA decay, or ameliorating one or more symptoms associated therewith.

REFERENCES:
patent: 3192103 (1965-06-01), Sousa et al.
patent: 3325446 (1967-06-01), Chang et al.
patent: 4016170 (1977-04-01), Nadelson
patent: 4022901 (1977-05-01), Narayanan et al.
patent: 4135910 (1979-01-01), Howe
patent: 4166732 (1979-09-01), Howe
patent: 4210762 (1980-07-01), Howe
patent: 4268299 (1981-05-01), Howe
patent: 4414221 (1983-11-01), Parsons et al.
patent: 5484944 (1996-01-01), Albaugh et al.
patent: 5972050 (1999-10-01), Wiesenfeldt et al.
patent: 6034106 (2000-03-01), Biftu et al.
patent: 6180648 (2001-01-01), Kozikowski et al.
patent: 6472422 (2002-10-01), Kozikowski et al.
patent: 6498151 (2002-12-01), Li et al.
patent: 6620828 (2003-09-01), Chu et al.
patent: 6660753 (2003-12-01), Van Wagenen et al.
patent: 6759538 (2004-07-01), Singh et al.
patent: 6878734 (2005-04-01), Kalindijian et al.
patent: 6992096 (2006-01-01), Karp et al.
patent: 7041685 (2006-05-01), Cai et al.
patent: 7112595 (2006-09-01), Van Wagenen et al.
patent: 7153880 (2006-12-01), Singh et al.
patent: 7202262 (2007-04-01), Karp et al.
patent: 2002/0025976 (2002-02-01), Chu et al.
patent: 2002/0055521 (2002-05-01), Kozikowski et al.
patent: 2002/0147188 (2002-10-01), Cummings
patent: 2005/0154012 (2005-07-01), Cai et al.
patent: 4320801 (1995-01-01), None
patent: 675122 (1995-10-01), None
patent: 51-143669 (1976-12-01), None
patent: 2001-247569 (2001-09-01), None
patent: 2002-105073 (2002-04-01), None
patent: WO 95/11885 (1995-05-01), None
patent: WO 97/09335 (1997-03-01), None
patent: WO 97/44333 (1997-11-01), None
patent: WO 97/46556 (1997-12-01), None
patent: WO 98/00465 (1998-01-01), None
patent: WO 98/33927 (1998-08-01), None
patent: WO 98/45263 (1998-10-01), None
patent: WO 98/49190 (1998-11-01), None
patent: WO 99/54317 (1999-10-01), None
patent: WO 00-21959 (2000-04-01), None
patent: WO 00-25768 (2000-05-01), None
patent: WO 00-38687 (2000-07-01), None
patent: WO 00-58278 (2000-10-01), None
patent: WO 00-58280 (2000-10-01), None
patent: WO 00-58304 (2000-10-01), None
patent: WO 00-69810 (2000-11-01), None
patent: WO 00-75120 (2000-12-01), None
patent: WO 01-66534 (2001-09-01), None
patent: WO 01-85723 (2001-11-01), None
patent: WO 01-90101 (2001-11-01), None
patent: WO 02-072621 (2002-09-01), None
patent: WO 02-085869 (2002-10-01), None
patent: WO 02/100826 (2002-12-01), None
patent: WO 03-002559 (2003-01-01), None
patent: WO 2004/014370 (2004-02-01), None
patent: WO 2004/014902 (2004-02-01), None
patent: WO 2004/072050 (2004-08-01), None
patent: WO 2004/110351 (2004-12-01), None
patent: WO 2005/060961 (2005-07-01), None
patent: WO 2005/077373 (2005-08-01), None
Mueller, G.,Chem. Ber., 19:1497 (1886).
U.S. Appl. No. 60/269,847, filed Feb. 21, 2001, Van Wagenen et al.
U.S. Appl. No. 60/149,464, filed Aug. 19, 1999, Van Wagenen et al.
U.S. Appl. No. 60/405,472, filed Aug. 23, 2002, Singh et al.
U.S. Appl. No. 60/350,107, filed Nov. 2, 2001, Singh et al.
Sokolenko et al., 1972, Voprosy Khimii I Khimicheskoi Tekhnolugii, No. 27:107-112 (with English language abstract).
Deegan et al., 1999, “Parallel Synthesis of 1,2,4-Oxadiazoles Using CDI Activation,” Bioorg. & Med. Chem. Lett. 9:209-212.
Carvalho et al., 1997, “Excited-state acidity of bifunctional compounds,” J. Chem. Soc., Faraday Trans. 93(18):3325-3329.
Bencharif et al., 1997, “Anodic behavior of aromatic oximes: an electrochemical deoximation reaction,” Electrochimica Acta. 42(23-24):3509-3512.
Fetizon et al., 1974, “Oxidations Par Le Carbonate D'Argent—XII,” Tetrahedron 31:165-170 (with English language abstract).
Haugwitz et al., 1985, “Antiparasitic Agents. 6. Synthesis and Anthelmintic Activites of Novel Isothiocyanatophenyl-1,2,4-oxadiazoles,” J. Med. Chem. 28:1234-1241.
Yurugi et al., 1973, “Studies of the Synthesis of N-Heterocyclic Compounds. IV. Hypocholesterolemic 1,2,4-Oxadiazole Derivatives,” Chem. Pharm. Bull. 21(9):1885-1893.

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