3-(4-piperidinyl)-2,3,4,5-tetrahydro-1,3-benzodiazepin-2(1H)...

Details 3-(4-piperidinyl)-2,3,4,5-tetrahydro-1,3-benzodiazepin-2(1H)... 3-(4-piperidinyl)-2,3,4,5-tetrahydro-1,3-benzodiazepin-2(1H)...

2006-11-28

2006-11-28

Kifle, Bruck (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

Reexamination Certificate

active

07141667

ABSTRACT:
The present invention relates to a process for preparing the compound 3-(4-piperidinyl)-2,3,4,5-tetrahydro-1,3-benzodiazepin-2(1H)-one of formulawhich is to be found as a structural element in CGRP-antagonists, which are particularly suitable for the oral treatment of migraine.

REFERENCES:
patent: 3474090 (1969-10-01), Wright, Jr.
patent: 2361939 (2000-09-01), None
patent: 0055154 (2000-09-01), None
Mayer, P. et al; New Substituted 1-(2,3-Dihydrobenzo[1,4]dioxin-2-ylmethyl)piperidin-4-yl Derivatives with a2-Adrenoceptor Antagonist Activity; Journal of Medicinal Chemistry, 2000, vol. 43, pp. 3653-3664.

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