3-(4-oxo-4H-chromen-2-yl)-(1H)-quinolin-4-one derivatives,...

Details 3-(4-oxo-4H-chromen-2-yl)-(1H)-quinolin-4-one derivatives,... 3-(4-oxo-4H-chromen-2-yl)-(1H)-quinolin-4-one derivatives,...

2003-06-18

2008-03-04

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S157000, C546S158000

Reexamination Certificate

active

07339061

ABSTRACT:
Compound of formula (I):wherein:R1, R2, R3, R4, R6, R8, R9and R10, which may be the same or different, each represent a group selected from hydrogen, hydroxy, alkoxy, alkyl, arylalkoxy, alkoxycarbonylalkoxy and OR′ wherein R′ represents an ionised or ionisable group,R5represents a group selected from alkyl, aryl and heteroaryl,R7represents a group selected from hydrogen, hydroxy, alkoxy, alkyl and cycloalkyl, or R7represents a nitrogen-containing or oxygen-containing heterocycle,its optical isomers, hydrates and solvates thereof and addition salts thereof, with a pharmaceutically acceptable acid or base.Medicinal products containing the same which are useful as anti-cancer agents.

REFERENCES:
Baczynski, CA 13L:12820, abstract only of Berichte der Deutschen Chemischen Gesellschaft, Abhandlungen, 52B, pp. 461-484, 1919.
Chemical Abstracts, vol. 123, No. 5, 1995, p. 906, abstract # 55705x.
International Search Report; PCT/FR03/01849; Sep. 26, 2003.
International Preliminary Examination Report; PCT/FR03/01849; Jan. 14, 2004.
International Preliminary Examination Report for PCT/FR2003/001849, May 18, 2006.

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