Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific...
Patent
1977-07-18
1978-09-19
Curtis, Allen B.
Drug, bio-affecting and body treating compositions
Nonspecific immunoeffector, per se ; or nonspecific...
542426, 542429, 26034855, C07C17700
Patent
active
041155807
ABSTRACT:
The disclosure relates to .omega.-aryl substituted .omega.-nor prostaglandin analogues bearing an oxygenated function at C-10, such as a hydroxy radical, or a 9,10- or 10,11-epoxide. A typical compound is 16-(3-chlorophenoxy)-9.alpha.,10.beta.,11.alpha.,15.alpha.-tetrahydroxy-17 ,18,19,20-tetranor-5-cis,13-trans-prostadienoic acid. Also disclosed are chemical processes for the manufacture of said compounds, pharmaceutical and veterinary compositions containing said compounds, and a method of achieving luteolysis in mammals by the use of such compounds.
REFERENCES:
patent: 3772350 (1973-11-01), Pike
patent: 3899526 (1975-08-01), Schneider
patent: 3931297 (1976-01-01), Crabbe
patent: 3933904 (1976-01-01), Strike
patent: 3966773 (1976-06-01), Bernady et al.
patent: 4028350 (1977-06-01), Biendy
Bowler Jean
Robinson Graham Ernest
Curtis Allen B.
Imperial Chemical Industries Limited
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