3,4-disubstituted-phenylsulphonamides and their therapeutic use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

546142, 546153, 546122, 5462771, 514312, 514415, 514418, 514259, 514419, 514416, 514300, 514248, 548491, 548509, 548485, 548492, 548482, 548472, 544287, 544286, 544237, C07D21708, C07D21724, A61K 31435

Patent

active

057287120

ABSTRACT:
3,4-Disubstituted-phenylsulphonamides have therapeutic utility via TNF or phosphodiesterase inhibition.

REFERENCES:
patent: 4289772 (1981-09-01), Campbell et al.
patent: 4720580 (1988-01-01), Buzby, Jr.
patent: 4804673 (1989-02-01), Saito et al.
patent: 4906640 (1990-03-01), Schoen et al.
patent: 4948809 (1990-08-01), Witte et al.
patent: 5338851 (1994-08-01), Huff et al.
patent: 5397801 (1995-03-01), Wagnon et al.
patent: 5446065 (1995-08-01), Witte et al.
Athanasiou, C. et al. (1984) "Synthesis of benzenesulfonamide and benzenesulfonohydrazide derivatives. Their effect on Phytopathogenic fungi." Eur. J. Med. Chem. 19(3):281-282.
Dauksas, V., O. Kersulis (1964) "Synthesis of N-substituted 1,4-benzodioxane-6- and veratrol-4-sulfonamides" Chemical Abstracts 61(11):13304.
Buckle, D.R. et al. (1994) "Inhibition of Cyclic Nucleotide Phosphodiesterase by Derivatives of 1,3-Bis (cyclopropylmethyl) xanthine" J. Med. Chem. 37:476-485.
Gaggero, N. et al. (1994) "Oxidation of SR 48117, an antagonist of vasopressin V.sub.1a receptors, by biomimetric catalysts based on metalloporphyrin or Schiff-base complexes" Bull Soc. Chim Fr 131:706-712.
Ohshima, E. et al. (1992) "Non-Prostanoid Thromboxane A.sub.2 Receptor Antagonists with a Dibenzoxepin Ring System. 1" J. Med. Chem. 35:3394-3402.
Soyka, R. et al. (1994) "6,6-Disubstituted Hex-5-enoic Acid Derivatives as Combined Thromboxane A.sub.2 Receptor Antagonists and Synthetase Inhibitors" J. Med. Chem. 37:26-39.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

3,4-disubstituted-phenylsulphonamides and their therapeutic use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3,4-disubstituted-phenylsulphonamides and their therapeutic use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3,4-disubstituted-phenylsulphonamides and their therapeutic use will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-957970

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.