3, 4-diphenyl chromans for inhibiting one or more psychiatric di

Details 3, 4-diphenyl chromans for inhibiting one or more psychiatric di 3, 4-diphenyl chromans for inhibiting one or more psychiatric di

1997-02-20

1998-05-26

Spivack, Phyllis G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514422, A61K 3135, A61K 3141

Patent

active

057565392

ABSTRACT:
A method of inhibiting one or more psychiatric disorders is disclosed comprising administering a compound of formula I ##STR1## wherein R.sup.1, R.sup.4 and R.sup.5 are individually hydrogen, hydroxy, halogen, trifluoromethyl, C.sub.1-6, alkyl, C.sub.1-6 alkoxy or (tertiary amino)C.sub.1-6 alkoxy; and R.sup.2 and R.sup.3 are individually hydrogen or C.sub.1-6 alkyl, or a pharmaceutically acceptable salt thereof.

REFERENCES:
patent: 3340276 (1967-09-01), Carney et al.
patent: 3822287 (1974-07-01), Bolger
patent: 4447622 (1984-05-01), Salman et al.
patent: 5280040 (1994-01-01), Labroo et al.
patent: 5453442 (1995-09-01), Bryant et al.
Ray, S. et al., Jour. of Med. Chem., vol. 19, No. 2, pp. 276-279 (1976).
Abstract--Jour. of Bone and Mineral Res., vol. 9, Supple. 1, p. S394, 1994.
Sankaran, M.S. et al., Contraception, vol. 9, No. 3, pp. 279-289, 1974.
Grubb, G.S., Obstetrics and Gynecology, vol. 3, pp. 491-495, 1991.
Singh, M.M. et al., Acta. Endocrinologica, vol. 126, pp. 444-450, 1992.
Ray et al., IN 129187, Council of Scientific & Industrial Research (Government of India) Aug., 1975.
Mortola, J.F., Current Opinion in Endocrinology and Diabetes, vol. 2, pp. 483-492 (1995).
Chak, I.M. et al., Indian Jour. of Exper. Biol., vol. 15, pp. 1159-1161 1977).
Nemeroff, C. B., Neuropsychopharmacology, vol. 6, No. 2, pp. 69-75 (1992).
Nerozzi, D., et al., J. Endocrinol. Invest. vol. 11, pp. 697-701, (1988).
Glowa, J.R., et al., Prog. Neuro-Psychopharmacol. & Biol. Psychiat., vol. 15, pp. 379-391 (1991).
Grino, M. et al., Endocrine, vol. 3, pp. 395-398, (1995).
Fink et al., Cellular and Molecular Neurobiology, vol. 16, pp. 337-344 (1996).
Bartus, R.T. et al., Science, vol. 217, pp. 408-417 (1982).
Gould, E. et al., The Journal of Neuroscience, vol. 10, pp. 1286-1291 (1990).
Kampen, D.L. et al., Obstetrics & Gynecology, vol. 83, No. 6, pp. 979-983 (1994).
Phillips, S.M. et al., Psychoneuroendocrinology, vol. 17, No. 5, pp. 485-495 (1992).

Affiliated with

Also associated with

Rating

3, 4-diphenyl chromans for inhibiting one or more psychiatric di does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3, 4-diphenyl chromans for inhibiting one or more psychiatric di, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3, 4-diphenyl chromans for inhibiting one or more psychiatric di will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1960741