3,4-dihydroxychalcone derivatives

Details 3,4-dihydroxychalcone derivatives 3,4-dihydroxychalcone derivatives

1993-06-09

1994-01-04

Reamer, James H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514685, 568334, 564443, A61K 31135

Patent

active

052760588

ABSTRACT:
Novel 3,4-dihydroxychalcone derivatives useful as a pharmaceutical material, and novel anti-inflammatory preparations. The 3,4-dihydroxychalcone derivatives are compounds of the formula [I], ##STR1## wherein X is a substituted phenyl group represented, e.g., by the formula (i), ##STR2## in which R.sup.1 is a hydrogen atom or an alkyl group and R.sup.2 is an alkyl group, an alkoxy group or an --OH group (excluding an OH-group in the 4-position)
or salts thereof. The anti-inflammatory preparations contain one of the above 3,4-dihydroxychalcone derivatives as an active ingredient.

REFERENCES:
patent: 3137621 (1964-06-01), Lafon
patent: 4219569 (1980-08-01), Glenn
patent: 4279930 (1981-07-01), Hall et al.
patent: 4605674 (1986-08-01), Fujiu et al.

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