3,4-dihydroisoquinoline derivative compound and a...

Details 3,4-dihydroisoquinoline derivative compound and a... 3,4-dihydroisoquinoline derivative compound and a...

2005-10-18

2005-10-18

Davis, Zinna Northington (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S307000, C546S139000, C546S146000, C544S105000

Reexamination Certificate

active

06956033

ABSTRACT:
A 3,4-dihydroisoquinoline derivative compound of formula (I) or a non-toxic salt thereof and a pharmaceutical agent comprising it as active ingredient (wherein all symbols have the same meaning as described in the specification). The compound of formula (I) has agonizing activity on CB2 receptor and therefore it is useful for the prophilaxis and/or treatment of various diseases such as asthma, nasal allergy, atopic dermatitis, autoimmune diseases, rheumatoid arthritis, immune dysfunction, postoperative pain, carcinomatous pain, etc.

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Partial European Search Report dated Jul. 21, 2004.
Mikhailovskii, A.G. et al., Reaction of Enamines of the Isocholine and Phenanthridine Series with Oxalyl Chloride, (1994), vol. 30, No. 7, pp. 946-949.
A.G. Mikhailovsky, et al., “Reaction of Isoquinoline and Phernanthridine Enamines with Oxalyl Chloride”, (1994), No. 7, pp. 946 to 949.

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