3-,4-Dihydroimidazo (3,4-c)-1,3-pyrimidines and 4,5-dihydroimida

Details 3-,4-Dihydroimidazo (3,4-c)-1,3-pyrimidines and 4,5-dihydroimida 3-,4-Dihydroimidazo (3,4-c)-1,3-pyrimidines and 4,5-dihydroimida

1981-06-03

1983-03-01

Lee, Mary C.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

544281, 548324, C07D47108, C07D48708

Patent

active

043754350

ABSTRACT:
This invention relates to a process for preparing imidazolylalkylguanidines, in particular N-[3-(4-imidazolyl)propyl]-N'-[2-(5-methyl-4-imidazolylmethylthio)ethyl]gu anidine (impromidine) which has histamine H.sub.2 -agonist activity, to intermediates for use in this process and to processes for preparing these intermediates.

REFERENCES:
patent: 4013659 (1977-03-01), Durant et al.
patent: 4233302 (1980-11-01), Martin-Smith et al.
Derwent Abstracts 33126C (EP 10418), 53014B (EP 2930).
Ackermann et al., "Comparison Isomeric Ring Systems . . . ", Chem. Abst. 61:5638(c).

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