Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-03-25
2008-03-25
Wilson, James O. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S266240, C514S266400, C544S284000, C544S292000
Reexamination Certificate
active
11399790
ABSTRACT:
The present invention relates to compounds of formulawhereinR1, R2, and n are as defined hereinand to pharmaceutically acceptable acid addition salts thereof.The compounds of formula I have a good activity on the 5-HT5Areceptor. Therefore, the invention provides the use of a compound of formula I for 5-HT5Areceptor related diseases, such as anxiety, depression, sleep disorders and schizophrenia.
REFERENCES:
patent: 4379929 (1983-04-01), Conrad et al.
patent: 5444062 (1995-08-01), Coe et al.
patent: 5948775 (1999-09-01), Koko et al.
patent: 0 087 337 (1983-08-01), None
patent: WO 92/07844 (1992-05-01), None
patent: WO 2004/096771 (2004-11-01), None
Hoyer, et al., Pharmacol. Rev. vol. 46, pp. 157-204 (1994).
Rees et al., FEBS Letters, vol. 355, pp. 242-246 (1994).
Francken et al., Eur. J. Pharmacol. vol. 361, pp. 299-309 (1998).
Noda, et al., J. Neurochem. vol. 84, pp. 222-232 (2003).
Dubertret et al., Journal of Psychiatric Research, vol. 38, pp. 371-376 (2004).
Manetsch, et al., Chem. Eur. J., vol. 10, pp. 2487-2506 (2004).
Kosasayama, et al., Chem. Pharm. Bull. vol. 27(4), pp. 880-892 (1979).
Webb, T. et al,Bioorganic and Medicinal Che. Ltrs, vol. 11, 77-85 (2003) XP-002391791.
Alanine Alexander
Gobbi Luca Claudio
Kolczewski Sabine
Luebbers Thomas
Peters Jens-Uwe
Hoffmann-La Rochse Inc.
Johnston George W.
Prior Kimberly J.
Rocha-Tramaloni Patricia S.
Truong Tamthom N
LandOfFree
(3,4-dihydro-quinazolin-2-yl)-indan-1-yl-amines does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with (3,4-dihydro-quinazolin-2-yl)-indan-1-yl-amines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and (3,4-dihydro-quinazolin-2-yl)-indan-1-yl-amines will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3928993