3,4-dihydro-2H-1-benzopyran derivatives

Details 3,4-dihydro-2H-1-benzopyran derivatives 3,4-dihydro-2H-1-benzopyran derivatives

1984-05-29

1988-11-15

Chan, Nicky

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549407, 549405, C07D31160, A61K 3135

Patent

active

047850175

ABSTRACT:
The invention relates to compounds of the formula ##STR1## wherein R.sup.1 is hydrogen or lower alkyl; R.sup.2 is hydrogen or halogen; R.sup.3, R.sup.4 and R.sup.5 are hydrogen, acyl or lower alkyl; R.sup.6 and R.sup.7, independently, are hydrogen or lower alkyl; X is alkylene.sub.3-7 ; and n is an integer of zero to four; provided that only one of R.sup.3, R.sup.4 or R.sup.5 can be acyl;
enantiomers thereof, and, when R.sup.7 is hydrogen, salts thereof with pharmaceutically acceptable bases.
The compounds of formulas I and II are useful as agents for the treatment of allergic conditions.

REFERENCES:
patent: 4511685 (1985-04-01), Nissen et al.

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